David Beckham, a product of the club's famed youth system, left United in 2003 to join Real Madrid after making 265 appearances in 12 trophy-laden years in Manchester.Following a surprise move to LA Galaxy his best years appeared to be behind him but two subsequent loan switches to Milan have catapulted him back into the spotlight, for football reasons, and rejuvenated his international career.
Ahead of what are likely to be an engaging couple of games he has spoken of what it will mean to play against a club forever close to his heart.
"When I was at Real Madrid it just never felt right to come back to Old Trafford," he told Inside United magazine.
"The thought of playing United always gives me that sick feeling because I missed the club so much.
"The first few years away were hard and there were a lot of things I missed. It was the club I always wanted to play for and I loved every minute of my time there.
"I always wish I was part of Manchester United, it's just in me. Even though I'm not there any more, I'm still a huge fan and watch every game where possible.
"I always want them to do well and be successful because the club still means so much to me.
"When the draw was made it just felt it was the right time to go back. There isn't one player I'm particularly looking forward to facing. I'm just looking forward to being a part of it all and savouring the atmosphere in both games.
"Returning to Old Trafford is going to be special and a very emotional night. I've spoken to Gary Neville since the draw and we both believe it's going to be a great tie."